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Acetazolamide for Prevention of Acute Mountain Sickness (AMS)

Acupuncture for Frequent Tension-Type Headaches

Anti-Hypertensives to Prevent Death, Heart Attacks, and Strokes

Antibiotics for Cirrhotics with Upper GI Bleeds

Antibiotics for COPD Exacerbation

Antibiotics for Culture‐Positive Asymptomatic Bacteriuria in Pregnant Women

Antibiotics for Exacerbations of Chronic Obstructive Pulmonary Disease

Antibiotics for Infection Prevention In Ventricular Shunt Placement

Antibiotics for Open Fractures

Antiplatelet Agents for Acute Stroke

Antiplatelet Agents for Preventing Early Recurrence of Ischemic Stroke or Transient Ischemic Attack

Aspirin after Acute Ischemic Stroke

Aspirin for Cardiovascular Prevention (After Prior Heart Attack or Stroke)

Aspirin For Major Heart Attack (STEMI)

Atraumatic versus Conventional Needles for Lumbar Puncture

Bisphosphonates for Fracture Prevention in Post-Menopausal Women With Prior Fractures or Very Low Bone Density

Buprenorphine Maintenance vs. Placebo for Opioid Dependence

Chewing Gum for Reducing Post-Cesarean Section Ileus

Clopidogrel Added to Aspirin During and After a Coronary Event or Stenting

Clopidogrel for Cardiovascular Prevention (After Prior Heart Attack or Stroke)

Coadministration of Probiotics With Prescribed Antibiotics for Preventing Clostridium difficile Diarrhea

Combined Inhaled Short-Acting Beta2 Agonist and Anticholinergic Agents for Asthma

Continuous vs. Intermittent Beta Agonists for Asthma Attack

Corticosteroids for Sore Throat

Corticosteroids for the Treatment of Kawasaki Disease in Children

Corticosteroids for Treating Pneumonia

Cranberry Products for Preventing Urinary Tract Infections

Defibrillation for Cardiac Arrest

Direct Oral Anticoagulants vs. Conventional Anticoagulants for Deep Vein Thrombosis

Direct Oral Anticoagulants vs. Conventional Anticoagulants for Pulmonary Embolism

Early Endovascular Thrombectomy for Large-vessel Ischemic Stroke Reduces Disability at 90 Days

Elastic Stockings for Deep Vein Thrombosis Prevention After Surgery

Elastic Stockings Plus Medical Therapy for Deep Vein Thrombosis Prevention After Surgery

Endovascular thrombectomy for ischemic stroke beyond 6 hours from onset of symptoms

Epley Maneuver (Canalith Repositioning) for Benign Positional Vertigo

Erythromycin for Improved Upper Endoscopy

Erythromycin for Urgent Endoscopy After Upper Gastrointestinal Bleeding

Flexible Sigmoidoscopy or Fecal Occult Blood Testing for Colorectal Cancer Screening in Asymptomatic Individuals

Glatiramer Acetate (Copaxone) for Multiple Sclerosis

Glucocorticoid for Croup in Children

HPV vaccines for prevention of cervical pre-cancer in adolescent girls and women

Hypothermia for Neuroprotection After Cardiac Arrest

Ibuprofen for Treatment of Episodic Tension-Type Headaches

Ibuprofen vs. Acetaminophen for Fever or Pain in Children Younger Than Two Years

Inhaled Epinephrine, Steroids for Bronchiolitis

Intravenous Magnesium Sulfate for Acute Asthma Exacerbation in Adults

Lidocaine for Reducing Pain on Injection of IV Propofol

Lung-protective Ventilation for Acute Respiratory Distress Syndrome

Magnesium for Pre-Eclampsia

Medical Expulsive Therapy (Alpha Blockers) for Urological Stone Disease

Mediterranean Diet for Post Heart-Attack Care

Mu-Opioid Antagonists for the Treatment of Opioid-Induced Bowel Dysfunction

Nebulized Hypertonic Saline for Bronchiolitis in Infants

Nebulized Ipratropium for Asthma Attack

Nicotine Replacement Therapy for Smoking Cessation

Non-Invasive Positive Pressure Ventilation for Exacerbation of Chronic Obstructive Pulmonary Disease

Noninvasive Positive Pressure Ventilation for Cardiogenic Pulmonary Edema

Ondansetron (Zofran) for Pediatric Gastroenteritis

Opiate Analgesia for Acute Abdominal Pain

Opiates During Abdominal Pain Evaluation

Oral NSAIDs for Perineal Pain in the Early Postpartum Period

Peripheral Nerve Block for Hip Fracture

Pregabalin (Lyrica) for Acute Fibromyalgia Pain

Probiotics for Acute Infectious Diarrhea

Prophylactic Antibiotics In Cirrhotic Patients With Upper Gastrointestinal Bleeding

Rhogam Postpartum for Prevention of Sensitization in At-Risk Women

SGLT-2 Inhibitors and GLP-1 Receptor Agonists for Type 2 Diabetes

Statins for Heart Disease Prevention (With Known Heart Disease)

Steroids for Asthma Attack

Steroids for Croup

Steroids for Meningitis

Steroids for PCP/PJ Pneumonia

Steroids for Pharyngitis

Steroids for Prevention of Migraine Recurrence

Strength and Balance Programs for Elderly Falls

Subcutaneous Sumatriptans for Acute Migraine Attacks in Adults

Surgical Decompression for Space-Occupying Hemispheric Infarction

Systemic Corticosteroids for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)

Tap Water for Wound Irrigation

Tenofovir for Prevention of HIV Infection

The Efficacy and Safety of Colchicine for Pericarditis

Thrombolytics for Major Heart Attack (STEMI)

Tissue Plasminogen Activator (tPA) For Acute Ischemic Stroke

Topical Antibiotics for Clinical and Microbiologic Cure of Bacterial Conjunctivitis

Topical NSAIDs for Acute Musculoskeletal Pain in Adults

Topiramate (Topamax) for Migraine Prophylaxis

Tranexamic Acid for Severe Trauma

Tranexamic Acid for the Treatment of Epistaxis

Vaccines for Preventing Influenza in Healthy Individuals

Valproate for Adult Migraine Prophylaxis

Varenicline for Smoking Cessation

Video Laryngoscopy vs. Direct Laryngoscopy

Vitamin D for Fracture Prevention (Elderly, Nursing Home)

Warfarin for Atrial Fibrillation Stroke Prevention

Warfarin vs. Aspirin For Atrial Fibrillation Stroke Prevention